Changes over time in lipid profile variables in the entire group of 71 patients under HCQ treatment.
| Baseline, mean (SD) | 6 Months, mean (SD) | 12 Months, mean (SD) | p1 | 36 Months, mean (SD) | p2 | 60 Months, mean (SD) | p3 | |
|---|---|---|---|---|---|---|---|---|
| TC, mg/dl | 220 (41) | 213 (40) | 206 (39) | 0.01 | 207 (34) | 0.004 | 206 (32) | 0.006 |
| HDL, mg/dl | 57 (14) | 59 (14) | 61 (14) | 0.003 | 64 (15) | < 0.001 | 67 (17) | < 0.001 |
| LDL, mg/dl | 140 (39) | 134 (36) | 125 (33) | 0.066 | 124 (31) | 0.009 | 119 (28) | 0.099 |
| TG, mg/dl | 110 (47) | 105 (47) | 102 (37) | 0.821 | 102 (44) | 0.211 | 102 (48) | 0.357 |
| Atherogenic Index (TC/HDL) | 4.0 (1.3) | 3.8 (1.1) | 3.5 (0.8) | 0.001 | 3.4 (0.9) | < 0.001 | 3.3 (0.9) | < 0.001 |
↵1 Comparison of lipid profile variables between baseline and 12 months;
↵2 comparison of lipid profile variables between baseline and 36 months;
↵3 comparison of lipid profile variables between baseline and 60 months. TC: total cholesterol, HDL: high-density lipoprotein cholesterol, LDL: low-density lipoprotein cholesterol, TG: triglycerides.