Characteristics | Partial R (95% CI) | p |
---|---|---|
Cardiovascular risk factors | ||
Current smoking | 0.28 (−0.07 to 0.63) | 0.1 |
Body mass index | −0.15 (−0.55 to 0.22) | 0.4 |
Systolic blood pressure | 0.04 (−0.31 to 0.40) | 0.8 |
Diastolic blood pressure | 0.00 (−0.40 to 0.40) | 1.0 |
Total cholesterol | −0.50 (−0.82 to −0.18) | 0.004† |
HDL cholesterol | −0.26 (−0.65 to 0.09) | 0.1 |
LDL cholesterol | −0.48 (−0.80 to −0.16) | 0.007† |
Triglycerides* | 0.06 (−0.31 to 0.43) | 0.7 |
Glucose | −0.01 (−0.31 to 0.30) | 1.0 |
Insulin* | −0.15 (−0.53 to 0.24) | 0.4 |
HOMA-IR* | 0.09 (−0.34 to 0.52) | 0.7 |
Framingham score* | 0.18 (−0.18 to 0.55) | 0.3 |
RA characteristics | ||
Disease duration | 0.14 (−0.22 to 0.51) | 0.4 |
Rheumatoid factor–positive | −0.19 (−0.55 to 0.18) | 0.3 |
Disease activity score in 28 joints | 0.18 (−0.19 to 0.54) | 0.3 |
Tender joints* | 0.14 (−0.23 to 0.50) | 0.5 |
Swollen joints | 0.02 (−0.36 to 0.40) | 0.9 |
VAS patient disease activity | 0.13 (−0.23 to 0.49) | 0.5 |
Cumulative prednisone use | −0.23 (−0.62 to 0.16) | 0.2 |
Systemic inflammation | ||
Erythrocyte sedimentation rate | 0.16 (−0.34 to 0.87) | 0.4 |
C-reactive protein* | 0.31 (−0.05 to 0.66) | 0.09 |
Adipokines | ||
Adiponectin* | 0.06 (−0.30 to 0.40) | 0.8 |
Resistin* | 0.13 (−0.27 to 0.57) | 0.5 |
Leptin* | −0.25 (−0.61 to 0.11) | 0.2 |
Ghrelin* | 0.24 (−0.11 to 0.60) | 0.2 |
Associations were assessed in mixed regression models (age at time of the study was replaced by age at disease onset in the model that included disease duration).
↵† Statistically significant associations.
↵* Non-normally distributed variables that were logarithmically transformed prior to entering them in the models. HDL: high-density lipoprotein LDL: low-density lipoprotein; HOMA-IR: homeostasis model of insulin resistance; VAS: visual analog scale.