Characteristics at study entry of 40 patients with clinically active JIA. Except where otherwise indicated, values are median (interquartile range).
| All Patients, n = 40 | |
|---|---|
| Clinical characteristics | |
| No. (%) female | 25 (62.5) |
| Age at study visit, yrs, mean (SD) | 12.2 (2.8) |
| Disease duration at study visit, yrs | 2.3 (0.7–5.0) |
| PGA of overall disease activitya | 31 (20–48) |
| Patient’s global assessment of overall well beinga | 17 (1–48) |
| Patient’s pain assessmenta | 26 (3–67) |
| CHAQ scoreb | 0.625 (0.125–1.124) |
| No. active joints | 2 (1–3) |
| No. joints with limited range of motion | 1 (0–2) |
| ESR, mm/hc | 5 (2–8) |
| CRP, mg/dld | 1 (1–1) |
| JAMRIS scores, mean (min–max) | |
| Synovial hypertrophy, 0–12 | 2.03 (0–12) |
| Bone marrow changes, 0–24 | 0.85 (0–7) |
| Cartilage lesions, 0–24 | 0.08 (0–2) |
| Bone erosions, 0–24 | 0.05 (0–1) |
↵a Measured on a 0–100 mm visual analog scale (0 = best, 100 = worst).
↵b Units; 0 = best, 3 = worst.
↵c Normal < 15 mm/h.
↵d Normal < 0.6 mg/dl.
PGA: physician’s global assessment; ESR: erythrocyte sedimentation rate; CRP: C-reactive protein; JIA: juvenile idiopathic arthritis; CHAQ: Childhood Health Assessment Questionnaire; JAMRIS: Juvenile Arthritis Magnetic Resonance Imaging Scoring system.