Genetic interaction analysis between BANK1 and BLK polymorphisms with systemic lupus erythematosus. The attributable proportion due to interaction (AP) was 0.36; and the relative excess risk due to interation (RERI) was 0.17.
| BANK1 | BLK | |
|---|---|---|
| rs10516487 AA+AG | rs2736340 CC+CT | rs2736340 TT |
| No. cases/controls | 35/56 | 61/67 |
| p | — | 0.18 |
| OR (95% CI) | 1.0 (reference) | 1.46 (0.84–2.52) |
| rs10516487 GG | ||
| No. cases/controls | 156/191 | 246/185 |
| p | 0.27 | 1.21 × 10−3 |
| OR (95% CI) | 1.31 (0.82–2.10) | 2.13 (1.34–3.38) |