Disease activity, functional and structural outcome in the ESPOIR cohort over 5 years. Data are mean ± SD except where indicated.
| Baseline, n = 813 | Month 6, n = 757 | Month 12, n = 731 | Month 24, n = 692 | Month 36, n = 636 | Month 60, n = 573 | Baseline*, n = 573 | |
|---|---|---|---|---|---|---|---|
| DAS28 | 5.1 ± 1.3 | 3.4 ± 1.4 | 3.1 ± 1.4 | 2.9 ± 1.4 | 2.9 ± 1.4 | 2.7 ± 1.3 | 5.1 ± 1.3 |
| Swollen joints, n | 7.2 ± 5.4 | 2.4 ± 3.3 | 2.1 ± 3.1 | 1.6 ± 3 | 1.3 ± 2.5 | 1.2 ± 2.5 | 7.5 ± 5.4 |
| Tender joints, n | 8.4 ± 7.0 | 4.4 ± 5.8 | 3.7 ± 5.6 | 2.9 ± 5.2 | 3.0 ± 5.3 | 2.7 ± 5 | 8.4 ± 6.9 |
| Patient global assessment | 59.8 ± 25.6 | 34.7 ± 26.8 | 31.1 ± 26.4 | 28.0 ± 26.4 | 28.8 ± 26.2 | 25.9 ± 25.4 | 59.3 ± 25.6 |
| HAQ-DI score | 1.0 ± 0.7 | 0.5 ± 0.6 | 0.5 ± 0.6 | 0.5 ± 0.6 | 0.5 ± 0.6 | 0.5 ± 0.6 | 1 ± 0.7 |
| ESR, mm/h | 29.4 ± 24.6 | 16.2 ± 14.0 | 15.2 ± 13.8 | 15.6 ± 14 | 14.9 ± 13.2 | 14.5 ± 13.3 | 28.8 ± 24.3 |
| CRP level, mg/dl | 20.3 ± 32.4 | 22.2 ± 33.6 | 8.8 ± 19.9 | 7.4 ± 12.2 | 7.0 ± 12.6 | 6.8 ± 11.7 | 22.0 ± 34.8 |
| mTS** score | 4.9 ± 7.1 | 10.7 ± 1.3 | 13.8 ± 14.7 | 5.3 ± 6.8 | |||
| Erosion score | 1.4 ± 3.6 | 3.1 ± 7.4 | 4.0 ± 7.8 | 1.6 ± 3.4 | |||
| Missing values, %*** | 0.25 | 0.24 | 0.16 | 0.23 | 0.64 | 0.65 | 0.23 |
↵* For patients with a visit at 5 years.
↵** van der Heijde-modified total Sharp score.
↵*** Any missing values that are not reported here, including those from quality-of-life and medicoeconomic questionnaires. DAS28: Disease Activity Score in 28 joints; HAQ-DI: Health Assessment Questionnaire-Disability Index; ESR: erythrocyte sedimentation rate; CRP: C-reactive protein.