Summary of regression analyses with phenotype as dependent variable.
| AUC | Severe, NA | Bone Density, 0.91 | Early, 0.79 | Late, 0.76 | No, 0.72 |
|---|---|---|---|---|---|
| Radiographic feature | |||||
| Minimum JSW | |||||
| Medial JSW | + | ||||
| Lateral JSW | − | ||||
| Varus angle | + | − | + | ||
| Osteophyte area | + | − | |||
| Eminence height | + | − | − | + | |
| Bone density | + | − | − | ||
| Demographic and clinical | |||||
| Age | + | ||||
| Female sex | − | + | |||
| Body mass index | − |
Area under receiver-operator characteristic curve (AUC-ROC) depicted for multivariate model with radiographic features, and demographic and clinical variables as dependent variables (measured at baseline). For the significant dependent variables + represents OR > 1 (and 95% CI > 1), and – represents OR < 1 (and 95% CI < 1). NA: multivariate analyses not performed because of limited n-value; JSW: joint space width.