Table 4.

Association between reduction in biomarker values between the 2 samples and TNFi treatment response in patients with psoriatic arthritis.

Biomarker	Univariate Model			Multivariate Model
				Full Model			Reduced Model
	OR	95% CI	p	OR	95% CI	p	OR	95% CI	p
MMP-3	1.107	0.987, 1.242	0.081	1.211	0.942, 1.557	0.135	1.213	1.019, 1.445	0.030
COMP	0.805	0.598, 1.083	0.151	0.490	0.247, 0.974	0.042	0.587	0.354, 0.973	0.039
hsCRP	1.113	0.900, 1.376	0.325	1.049	0.686, 1.604	0.827
RANKL	1.004	0.998, 1.010	0.209	1.006	0.998, 1.014	0.132
OPG	0.998	0.993, 1.003	0.476	0.997	0.989, 1.004	0.393
TNFSF14	1.004	0.999, 1.008	0.096	1.005	0.997, 1.014	0.236
CS-846	1.004	0.982, 1.026	0.739	0.980	0.944, 1.016	0.267
C1-2C	0.017	0.000, 4.672	0.155	0.000	0.000, 3.980	0.072
CPII	0.999	0.995, 1.003	0.584	1.000	0.989, 1.010	0.972
C2C	0.998	0.986, 1.010	0.781	1.045	0.999, 1.094	0.057

OR reflects the effect of having a 1-unit higher decrease of each biomarker, except for COMP, for which the OR reflects the effect of a 100-unit decrease; for abbreviations see Table 2.