Characteristic | CTD-ILD, n = 125 |
---|---|
Age, yrs | 60.4 ± 11.6 |
Female, n (%) | 52 (42) |
Ethnicity, n | |
White | 104 |
Black | 5 |
Hispanic | 11 |
Asian | 1 |
Other | 4 |
Smoking history, n (%) | |
Never | 77 (62) |
Former | 48 (38) |
Connective tissue disease, n | |
Systemic sclerosis | 44 |
Polymyositis/dermatomyositis | 32 |
Lung-dominant connective tissue disease | 19 |
Rheumatoid arthritis | 18 |
Sjögren disease | 5 |
Systemic lupus erythematosus | 4 |
Mixed connective tissue disease | 3 |
Mode of ILD diagnosis | |
Clinical/HRCT, n (%) | 74 (59) |
Surgical lung biopsy, n (%) | 51 (41) |
Pathological pattern, n | |
fNSIP | 17 |
fNSIP + OP | 10 |
UIP | 14 |
UIP + OP | 1 |
OP | 8 |
DIP | 1 |
Pulmonary physiology | |
FVC% | 66.7 ± 16.0 |
DLCO% | 47.4 ± 16.4 |
CTD-ILD: connective tissue disease-associated interstitial lung disease; HRCT: high-resolution computed tomography scan; DIP: desquamative interstitial pneumonia; fNSIP: fibrotic nonspecific interstitial pneumonia; OP: organizing pneumonia; UIP: usual interstitial pneumonia; FVC%: percent of predicted normal forced vital capacity for sex, ethnicity, age, and height; DLCO%: percentage of predicted normal diffusing capacity for sex, ethnicity, age, and height.