Characteristics of subjects at time of initiation of mycophenolate mofetil. Data are number (%) or mean ± SD.
| Characteristic | CTD-ILD, n = 125 |
|---|---|
| Age, yrs | 60.4 ± 11.6 |
| Female, n (%) | 52 (42) |
| Ethnicity, n | |
| White | 104 |
| Black | 5 |
| Hispanic | 11 |
| Asian | 1 |
| Other | 4 |
| Smoking history, n (%) | |
| Never | 77 (62) |
| Former | 48 (38) |
| Connective tissue disease, n | |
| Systemic sclerosis | 44 |
| Polymyositis/dermatomyositis | 32 |
| Lung-dominant connective tissue disease | 19 |
| Rheumatoid arthritis | 18 |
| Sjögren disease | 5 |
| Systemic lupus erythematosus | 4 |
| Mixed connective tissue disease | 3 |
| Mode of ILD diagnosis | |
| Clinical/HRCT, n (%) | 74 (59) |
| Surgical lung biopsy, n (%) | 51 (41) |
| Pathological pattern, n | |
| fNSIP | 17 |
| fNSIP + OP | 10 |
| UIP | 14 |
| UIP + OP | 1 |
| OP | 8 |
| DIP | 1 |
| Pulmonary physiology | |
| FVC% | 66.7 ± 16.0 |
| DLCO% | 47.4 ± 16.4 |
CTD-ILD: connective tissue disease-associated interstitial lung disease; HRCT: high-resolution computed tomography scan; DIP: desquamative interstitial pneumonia; fNSIP: fibrotic nonspecific interstitial pneumonia; OP: organizing pneumonia; UIP: usual interstitial pneumonia; FVC%: percent of predicted normal forced vital capacity for sex, ethnicity, age, and height; DLCO%: percentage of predicted normal diffusing capacity for sex, ethnicity, age, and height.