Table 4.

Predictors at first 5 years and 5-year followup associated with outcome at 17-year followup for 86 incidence cases of juvenile chronic arthritis. Univariate correlations with Spearman correlation coefficient are used for comparison between continuous and ordinal variables and chi-square test/Fisher exact test (FET) are used for comparison between categorical variables.

Variable17-year RemissionHAQKeitel Functional TestDMARDSF-36 PCSNo. Joints with ArthritisNo. Involved Joints
DADI 1 yrNSNSNSNSNSNSNS
DADI first 2 yrsNSNSrs −0.304; p = 0.005NSrs −0.247; p = 0.024NSrs 0.362; p = 0.001
DADI first 3 yrsrs −0.239; p = 0.027NSrs −0.355; p = 0.001rs 0.227; p = 0.038rs −0.280; p = 0.010NSrs 0.407; p < 0.001
DADI first 4 yrsrs −0.244; p = 0.024NSrs −0.418; p < 0.001rs 0.276; p = 0.011rs −0.283; p = 0.009NSrs 0.440; p < 0.001
5-years
  Activityrs −0.401; p < 0.001rs −0.301; p = 0.005rs −0.492; p < 0.001rs 0.478; p < 0.001rs −0.381; p < 0.001rs 0.378; p < 0.001rs 0.550; p < 0.001
  RemissionChi-square 9.544; p = 0.002rs −0.266; p = 0.014rs 0.460; p < 0.001FET p = 0.002rs −0.389; p < 0.001rs −0.344; p = 0.001rs −0.445; p < 0.001
  CHAQrs −0.352; p = 0.001rs 0.358; p = 0.001rs −0.494; p < 0.001rs 0.373; p = 0.001rs −0.406; p < 0.001rs 0.316; p = 0.004rs 0.382; p < 0.001
  DADIrs −0.266; p = 0.013rs 0.267; p = 0.014rs −0.486; p < 0.001rs 0.375; p < 0.001rs −0.322; p = 0.003rs 0.270; p = 0.012rs 0.477; p < 0.001
  Disease subgroupNSNSNSNSNSNSNS
  No. joints with arthritisNSNSrs −0.449; p < 0.001rs 0.341; p = 0.001rs −0.285; p = 0.008rs 0.360; p = 0.001rs 0.502; p < 0.001
  No. involved jointsrs −0.283; p = 0.008rs 0.251; p = 0.020rs −0.468; p < 0.001rs 0.412; p < 0.001rs −0.276; p = 0.010rs 0.280; p = 0.009rs 0.532; p < 0.001
Radiographic changesNSNSNSNSNSNSNS
RF positivityNSrs 0.250; p = 0.040rs −0.396; p = 0.001NSNSNSNS
  • HAQ: Health Assessment Questionnaire; DMARD: Disease-modifying Antirheumatic Drugs; SF-36 PCS: Medical Outcomes Study Short Form-36 physical component summary; DADI: Disease Activity Duration Index; CHAQ: Childhood Health Assessment Questionnaire; RF: rheumatoid factor; NS: not significant.