Combined allele frequencies and OR in patients with fibromyalgia syndrome (FM) and healthy controls. Statistical package PHASE v2.1.1 was used to construct haplotype structures; missing data were excluded (n = 4). Among 13 haplotype structures, the frequencies of 4 major haplotype structures are presented; the total frequency of the other haplotype structures was 29 (3.4%) for controls and 74 (9.1%) for patients. Logistic regression models were used to calculate OR.
| Combined Allele* | Healthy Controls n (%) | Patients with FM n (%) | p† | Crude OR (95% CI) | Age- and Sex-adjusted OR (95% CI) |
|---|---|---|---|---|---|
| CCTT | 460 (54.6) | 433 (53.1) | 0.11 | 1.00 (reference) | 1.00 (reference) |
| TTCT | 223 (26.5) | 187 (22.9) | 0.89 (0.71–1.13) | 0.88 (0.70–1.12) | |
| TTCA | 107 (12.7) | 112 (13.7) | 1.11 (0.83–1.50) | 1.11 (0.82–1.49) | |
| CCTA | 23 (2.7) | 10 (1.2) | 0.46 (0.22–0.98) | 0.45 (0.21–0.96) |