Relationship between cognitive function scores and physical function measures.
| Bivariate | Multivariate* | |||
|---|---|---|---|---|
| Score and Function | Std. ß** | p | Std. ß** | p |
| Global cognitive function | ||||
| Regression 1: SPPB† | −0.26 | 0.004 | −0.24 | 0.014 |
| Regression 2: HAQ | 0.33 | < 0.001 | 0.24 | 0.003 |
| Regression 3: VLA difficulty | 0.25 | 0.006 | 0.10 | 0.207 |
| Executive function | ||||
| Regression 1: SPPB† | −0.14 | 0.125 | −0.07 | 0.458 |
| Regression 2: HAQ | 0.29 | 0.001 | 0.16 | 0.046 |
| Regression 3: VLA difficulty | 0.22 | 0.016 | 0.04 | 0.603 |
| Memory function | ||||
| Regression 1: SPPB† | −0.24 | 0.008 | −0.25 | 0.009 |
| Regression 2: HAQ | 0.21 | 0.022 | 0.18 | 0.029 |
| Regression 3: VLA difficulty | 0.17 | 0.055 | 0.11 | 0.163 |
↵* Covariates: sex, race, education level, duration of rheumatoid arthritis (RA), severity of RA, cardiovascular comorbidity, and depression.
↵** Std. ß are for the effect of the independent variable (cognitive function scores) on each physical function measure (SPPB, HAQ, and VLA).
↵† On SPPB, lower scores reflect worse functioning; on HAQ and VLA, higher scores reflect worse functioning. SPPB: Short Physical Performance Battery; HAQ: Health Assessment Questionnaire; VLA: Valued Life Activities.