Demographic characteristics of patients with systemic sclerosis. Incidence of new digital ulcers is also reported at baseline (T0) and after 3 years (T3).
| Characteristic | ILO Group (15 patients) | ILO+BOS Group (15 patients) |
|---|---|---|
| Mean age, yrs | 63 ± 15 | 68 ± 13 |
| Mean SSc duration, yrs | 7 ± 3 | 8 ± 4 |
| Sex (male/female) | 1/14 | 2/13 |
| LSSc, n | 3 | 0 |
| LcSSc, n | 9 | 7 |
| DcSSc, n | 3 | 8 |
| ANA speckled pattern, % | 13 | 27 |
| ANA homogeneous, % | 13 | 40 |
| ANA nucleolar, % | 7 | 7 |
| ANA centromeric, % | 67 | 27 |
| Scl70-positive, % | 20 | 27 |
| New digital ulcers, n | ||
| T0 | 0/15 | 15/15* |
| T3 | 2/15 | 0/15 |
↵* Patients were enrolled in the ILO+BOS group upon the appearance of new digital ulcers. LSSc: limited systemic sclerosis; LcSSc: limited cutaneous systemic sclerosis; DcSSc: diffuse cutaneous systemic sclerosis; ILO: iloprost; BOS: bosentan; ANA: antinuclear antibodies.