Least-squares means (95% CI) of numbers and total scores of tender points in patients with fibromyalgia syndrome (n = 325) by guanosine triphosphate cyclohydrolase 1 gene single-nucleotide polymorphism genotype.
| Position* | Genotype | n† | No. Tender Points | Total Score of Tender Points |
|---|---|---|---|---|
| rs841 (C>T) | TT | 62 | 14.0 (13.0–15.0) | 28.5 (25.1–31.9) |
| CT | 144 | 14.4 (13.7–15.1) | 28.2 (25.9–30.5) | |
| CC | 119 | 13.4 (12.7–14.2) | 24.5 (22.1–26.9) | |
| p†† | 0.16 | 0.06 | ||
| rs752688 (C>T) | TT | 60 | 14.0 (13.0–15.0) | 27.5 (24.1–31.0) |
| CT | 153 | 14.4 (13.7–15.0) | 28.2 (26.0–30.4) | |
| CC | 112 | 13.4 (12.7–14.2) | 24.7 (22.2–27.2) | |
| p†† | 0.16 | 0.11 | ||
| rs4411417 (T>C) | CC | 57 | 14.1 (13.1–15.1) | 28.6 (25.0–32.1) |
| TC | 155 | 14.3 (13.7–14.9) | 27.7 (25.5–29.8) | |
| TT | 112 | 13.5 (12.8–14.3) | 25.1 (22.6–27.6) | |
| p†† | 0.28 | 0.20 | ||
| rs3783641 (T>A) | AA | 14 | 13.4 (11.3–15.5) | 22.3 (15.0–29.6) |
| TA | 77 | 13.5 (12.6–14.4) | 26.1 (23.0–29.2) | |
| TT | 234 | 14.2 (13.6–14.7) | 27.4 (25.6–29.1) | |
| p†† | 0.39 | 0.35 |