Clinical, demographic, and immunological data in 947 patients. Data are number (%) unless otherwise indicated.
| Characteristic | |
|---|---|
| Age at disease onset, mean (± SD), yrs | 42.6 (14.1) |
| Disease duration, mean (± SD), yrs | 12.9 (8.5) |
| Followup period, mean (± SD), yrs | 9.6 (7.7) |
| Race | |
| White | 838 (88.5) |
| African Brazilian | 109 (11.5) |
| Clinical variant | |
| Limited | 712 (75.2) |
| Diffuse | 235 (24.8) |
| Sine scleroderma | 79 (8.3) |
| mRSS < 20 | 635 (67.1) |
| ≥ 20 | 312 (32.9) |
| Calcinosis | 162 (17.1) |
| Telangiectasia | 464 (49.0) |
| Ulcers | 235 (24.8) |
| Osteoarticular involvement* | 452 (47.7) |
| Esophageal (hypomotility and/or GERD) | 897 (94.7) |
| Interstitial lung disease (ILD) | 538 (56.8) |
| Pulmonary hypertension (PH) | 221 (23.3) |
| ILD + PH | 132 (13.9) |
| Heart | 111 (11.7) |
| Renal crisis | 25 (2.6) |
| Antinuclear antibodies | 839 (88.6) |
| Anticentromere antibody | 209 (22.1) |
| Anti-Scl70 | 152 (16.1) |
↵* Inflammatory polyarthralgia or polyarthritis. mRSS: modified Rodnan skin score; GERD: gastroesophageal reflux disease.