Followup data of patients with chemotherapy-related arthropathy treated with nonsteroidal antiinflammatory drugs alone (NSAID-alone) and those treated with NSAID with hydroxychloroquine (HCQ). Data were analyzed by Wilcoxon signed-rank test; categorical values were compared by chi-square test.
| Initial | NSAID-alone After 3 Months | p | Initial | NSAID-HCQ After 3 Months | p | |
|---|---|---|---|---|---|---|
| Total patients, n (%) | 20 (100) | 14 (100) | ||||
| Morning stiffness, min | 461.1 ± 634.7 | 99.7 ± 290.1 | 0.24 | 455 ± 649.8 | 53.9 ± 85.6 | 0.094 |
| Pain VAS, mm | 5.1 ± 2.2 | 2.7 ± 2.3 | 0.004 | 5.3 ± 2 | 2.2 ± 1.7 | < 0.001 |
| Tender joint counts | 5.9 ± 4.7 | 2.0 ± 2.8 | 0.003 | 6.1 ± 6.5 | 0.8 ± 1.8 | 0.002 |
| Swollen joint counts | 1.4 ± 2.6 | 0.7 ± 1.6 | 0.496 | 3.1 ± 4.5 | 0.1 ± 2.9 | 0.106 |
| ESR, mm/hr | 13.2 ± 9.3 | 8.8 ± 8.5 | 0.132 | 30.9 = 23.4 | 12 ± 13.4 | 0.009 |
| CRP, mg/dl | 0.14 ± 0.13 | 0.09 ± 0.12 | 0.116 | 0.3 ± 0.35 | 0.07 ± 0.05 | 0.112 |
| Hemoglobin, g/dl | 12.4 ± 0.8 | 12.5 ± 1.1 | 0.74 | 12.8 ± 0.7 | 13.1 ± 0.7 | 0.154 |
| Leukocyte, μl | 4568 ± 1911 | 5335 ± 1759 | 0.08 | 4535 ± 1455 | 4630 ± 1155 | 0.841 |
| Steroid added, n (%) | 9 (45) | 5 (35.7) | ||||
| Other medication added, n (%) | 8 (40) | 6 (42.9) |
VAS: visual analog scale; ESR: erythrocyte sedimentation rate; CRP: C-reactive protein.