Table 2.

Distribution of inflammatory markers and positive prevalence.

RA with Complications
RA Flare, n = 18Noninfectious Complications, n = 23Nonbacterial Infections, n = 15Bacterial Infections, n = 62p
PCT, ng/ml, median (IQR)0.1 (0.1, 0.1)0.1 (0.1, 0.1)0.1 (0.1, 0.1)0.1 (0.1, 0.5)0.008
  ≥ 0.2 ng/ml, n (% [95% CI*])0 (0.0 [0.0–18.5])4 (17.4 [5.0–38.8])2 (13.3 [1.7–40.5])21 (33.9 [22.3–47.0])0.013
  ≥ 0.5 ng/ml, n (% [95% CI*])0 (0.0 [0.0–18.5])1 (4.3 [0.1–21.9])0 (0.0 [0.0–21.8])16 (25.8 [15.5–38.5])0.003
CRP, mg/dl, median (IQR)4.4 (2.75, 10.00)5.7 (2.80, 9.90)8.7 (1.85, 11.90)9.4 (4.45, 14.90)0.084
  ≥ 0.3 mg/dl, n (% [95% CI*])18 (100.0 [81.5–100.0])21 (91.3 [72.0–99.0])14 (93.3 [68.1–99.8])60 (96.8 [88.8–99.6])0.513
WBC, /mm3, median (IQR)8500 (6200, 9650)7900 (6700, 10,600)7500 (5450, 13,350)10,700 (7800, 14,800)0.003
  > 8500/mm3, n (% [95% CI*])7 (38.9 [17.3–64.3])9 (39.1 [19.7–61.5])7 (46.7 [21.3–73.4])41 (66.1 [53.0–77.7])0.053
ESR, mm/h, median (IQR)70 (61, 97.5)83 (50, 96)67 (35, 90.5)57 (40, 86)0.296
  ≥ 15 mm/h n (% [95% CI*])15 (83.3 [58.6–96.4])18 (78.3 [56.3–92.5])8 (53.3 [26.6–78.7])53 (85.5 [74.2–93.1])0.328
  • * Binomial distribution.

  • Kruskal-Wallis test for distribution of inflammatory markers and chi-square test for prevalence. IQR: interquartile range; PCT: serum procalcitonin; CRP: C-reactive protein; WBC: white blood cell count; ESR: erythrocyte sedimentation rate; RA: rheumatoid arthritis.