Table 7.

Univariate predictors of mortality in patients with connective tissue disease pulmonary artery hypertension.

VariablesHazard Ratio (95% CI)p
Age, yrs1.00 (0.95–1.05)0.93
mRAP, mm Hg1.2 (1.06–1.35)0.003
mPAP, mm Hg1.01 (0.96–1.06)0.009
mVO2, %0.91 (0.84–0.98)0.02
Cardiac index, l/min−1/m−20.59 (0.21–1.68)0.328
PVR, dyne/s/cm−51.00 (0.99–1.00)0.307
RVSV, ml/mm Hg−11.01 (0.98–1.04)0.186
RVEF0.99 (1.05–1.03)0.923
RVEDV, ml1.02 (1.01–1.03)0.002
RVEDM, g/cm31.03 (1.00–1.06)0.040
VMI5.56 (1.50–35.5)0.013
Pulmonary artery distensibility, %0.87 (0.64–1.18)0.388
Tricuspid gradient1.32 (0.33–5.30)0.68
  • RVEF: right ventricle ejection fraction; RVEDV: right ventricle end diastolic volume; RVESV: right ventricle end systolic volume; mRAP: mean right arterial pressure; mPAP: mean pulmonary artery pressure; PVR: pulmonary vascular resistance; mVO2: mixed venous saturation; RVEDM: right ventricular end diastolic volume; VMI: ventricular mass index.