Genotype and recessive and dominant models for the minor allele of TRAF6 rs540386 in global systemic sclerosis (SSc) and giant cell arteritis (GCA) compared with controls.
| Controls N (%) | SSc N (%) | p | OR (95% CI) | GCA N (%) | p | OR (95% CI) | |
|---|---|---|---|---|---|---|---|
| CC | 1102 (76.42) | 924 (77.97) | 364 (75.99) | ||||
| CT | 319 (22.12) | 244 (20.59) | 0.632* | NA | 111 (23.17) | 0.572* | NA |
| TT | 21 (1.46) | 17 (1.43) | 4 (0.84) | ||||
| CC + CT | 1421 (98.54) | 1168 (98.57) | 0.963 | 0.98 (0.51–1.88) | 475 (99.16) | 0.305 | 0.57 (0.19–1.67) |
| TT | 21 (1.46) | 17 (1.43) | 4 (0.84) | ||||
| CC | 1102 (76.42) | 924 (77.97) | 0.346 | 0.92 (0.76–1.10) | 364 (75.99) | 0.848 | 1.02 (0.80–1.31) |
| TT + CT | 340 (23.58) | 261 (22.03) | 115 (24.01) |
↵* P value for the genotype distribution. NA: not applicable.