Distribution of lung disease in ACPA-positive patients with RA.
| RA with Lung Disease | ||||
|---|---|---|---|---|
| Patient Group | RA without Lung Disease, n | Rheumatic Lung Disease*, n | Other Lung Disease**, n | Total |
| APF+, anti-CCP+ | 199 | 16 | 15 | 230 |
| APF+, anti-CCP– | 12 | 1 | 7 | 20 |
| APF–, anti-CCP+ | 134 | 14 | 13 | 161 |
| Total | 345 (83.9%) | 31 (7.6%) | 35 (8.5%) | 411 |
↵* Rheumatic lung disease includes interstitial pulmonary fibrosis, bronchiectasis, and rheumatoid nodules.
↵** Includes pulmonary involvement such as tuberculosis, atelectasis, pneumonia, focal inflammation, excepting rheumatic lung diseases. ACPA: anticitrullinated peptide/protein antibody; RA: rheumatoid arthritis; APF: antiperinuclear factor; CCP: cyclic citrullinated peptide.