Characteristic | Whole Group, n = 81 | No PH, n = 22 | PAH, n = 55 | p |
---|---|---|---|---|
Age, yrs | 62 (14) | 59 (16) | 64 (17) | 0.47 |
Female, % | 85 | 85 | 85 | 0.90 |
WHO II/III/IV, % | 25:63:9 | 40:55:0 | 20:66:13 | < 0.001 |
FVC, % predicted | 85 (22) | 91 (15) | 82 (24) | 0.11 |
TLCO, % predicted | 47 (19) | 67 (21) | 40 (12) | < 0.001 |
mRAP, mm Hg | 8 (5) | 6 (3) | 9 (5) | 0.007 |
mPAP, mm Hg | 35 (15) | 19 (3) | 40 (14) | < 0.001 |
PCWP, mm Hg | 9 (4) | 8 (3) | 8 (3) | 0.61 |
Cardiac index, l × min × m2 | 3.3 (0.8) | 3.7 (0.8) | 3.2 (0.7) | 0.004 |
PVR, dyn × s × cm−5* | 417 (393) | 112 (46) | 524 (404) | < 0.001 |
mVO2, % | 69 (8) | 73 (7) | 67 (8) | 0.008 |
FVC: forced vital capacity; TLCO: gas transfer; mRAP: mean right atrial pressure; mPAP: mean pulmonary artery pressure; PVR: pulmonary vascular resistance; mVO2: mixed venous oxygen saturation (n = 4 patients with LHD are included within the whole group); WHO: World Health Organization class; PCWP: pulmonary capillary wedge pressure; PAH: pulmonary arterial hypertension.