Table 2.

Organ involvement at onset (%).

EGPA Patients with IVIG, n = 22EGPA Patients without IVIG, n = 24p
Paranasal sinusitis10087NS*
Multiple polyneuropathy100100NS*
Minimum MMT score, mean ± SD2.6 ± 1.03.9 ± 0.8p < 0.01
Pulmonary infiltrates76.281.8NS*
Myocardial involvement78.947.80.04*
Gastrointestinal tract9058.30.02*
Liver, gall bladder, pancreas258.7NS*
Renal involvement**54.543.8NS*
  Eosinophils in urine36.435.3NS*
  Nephritis or nephrosis9.111.8NS*
Skin involvement66.761.9NS*
Central nervous system involvement13.625NS*
Extravascular eosinophils (pathology)90.983.3NS*
ACR 4 of the 6,5 of the 6,6 of the 61/6/153/8/13NS*
Cumulative organ involvement***, n, mean ± SD5.2 ± 1.94.5 ± 1.7NS
5-factor score2.1 ± 0.91.4 ± 0.8p < 0.01
  • Values of p < 0.05 considered statistically significant.

  • 2-way ANOVA with repeated measures among 2 groups.

  • * Chi-square testing revealed no significant differences in frequencies of the 2 groups.

  • ** Renal involvement including proteinuria, eosinophils in urine, glomerular nephritis, nephrosis, or renal dysfunction.

  • *** Cumulative organ involvement excluding asthma and sinusitis. EGPA: eosinophilic granulomatosis with polyangiitis; IVIG: intravenous immunoglobulin; NS: not significant; MMT: manual muscle test; ACR: American College of Rheumatology.