Allele frequencies of MEFV gene mutations in Japanese patients with FMF and healthy subjects.
| Allele Frequencies (%) | |||
|---|---|---|---|
| Alleles | Typical FMF, n = 28 | Probable FMF, n = 17 | Healthy Subjects, n = 75 |
| M694I | 19 (33.9)* | 0 | |
| P369S | 1 (1.8) | 5 (14.7)* | 6 (4.0) |
| R408Q | 1 (1.8) | 5 (14.7)* | 5 (3.3) |
| L110P | 3 (5.4) | 6 (17.6) | 13 (8.7) |
| E148Q | 18 (32.1) | 15 (44.1)* | 35 (23.3) |
| R202Q | 2 (3.6) | 2 (5.9) | 5 (3.3) |
| G304R | 0 | 1 (2.9) | 4 (2.7) |
| E84K | 4 (7.1)* | 2 (5.9) | 2 (1.3) |
↵* p ≤ 0.05 compared to healthy subjects. FMF: familial Mediterranean fever.