Baseline biological drug history in cases of anti-TNF failure. All data are n (%).
| History | Patients, n = 540 |
|---|---|
| Ever had etanercept | 238 (44.1) |
| Ever had infliximab | 138 (25.6) |
| Ever had adalimumab | 218 (40.4) |
| No. previous anti-TNF therapies | |
| 1 | 310 (57.4) |
| 2 | 182 (33.7) |
| 3 | 21 (3.9) |
| Not recorded | 27 (5.0) |
| Most recently stopped anti-TNF drug | |
| Etanercept | 232 (43.0) |
| Infliximab | 78 (14.4) |
| Adalimumab | 205 (38.0) |
| Not recorded | 25 (4.6) |
| Reason for stopping last biological therapy | |
| Inefficacy | 233 (43.1) |
| Adverse events | 117 (21.7) |
| Other | 42 (7.8) |
| Not recorded | 148 (27.4) |
TNF: tumor necrosis factor.