Risk Factors | OR (95% CI) | p |
---|---|---|
Fatty liver, n = 30/135 | ||
BMI | 1.170 (1.067, 1.283) | 0.001 |
Hypertension | 2.562 (1.011, 6.491) | 0.047 |
Triglyceride | 1.283 (1.042, 1.581) | 0.019 |
Aspirin | 6.000 (2.008, 17.924) | 0.001 |
NSAID | 5.333 (1.921, 14.810) | 0.001 |
Antimalarial | 2.885 (1.088, 7.649) | 0.032 |
IgG | 0.909 (0.841, 0.982) | 0.015 |
AST | 1.862 (0.509, 6.807) | 0.347 |
ALT | 4.833 (0.612, 38.190) | 0.135 |
ALP | 0.995 (0.986, 1.004) | 0.251 |
Drug-induced hepatoxicity, n = 34/135 | ||
Sex (female) | 2.667 (0.741, 9.599) | 0.133 |
SLE duration | 0.944 (0.898, 0.992) | 0.023 |
Arthritis | 0.465 (0.213, 1.018) | 0.055 |
Methotrexate | 2.377 (1.001, 5.642) | 0.050 |
Immunosuppressants | 2.377 (1.001, 5.642) | 0.050 |
SLICC damage index | 0.742 (0.560, 0.984) | 0.038 |
BMI: body mass index; NSAID: nonsteroidal antiinflammatory drug; AST: aspartate transaminase; ALT: alanine transaminase; ALP: alkaline phosphatase; SLE: systemic lupus erythematosus; SLICC: Systemic Lupus International Collaborating Clinics.