BASDAI, BASFI, BAS-G, ESR, and CRP levels in AS patients with IL-12B A1188C and IL-23R C2370A genotypes. Data are mean ± SD.
| Genotype | BASDAI | BASFI | BAS-G | ESR | CRP | |
|---|---|---|---|---|---|---|
| IL-12B | CC | 4.2 ± 2.3 | 2.3 ± 2.2 | 4.6 ± 2.9 | 24.8 ± 17.7 | 1.2 ± 1.8 |
| AC | 4.3 ± 2.3 | 2.4 ± 2.2 | 4.7 ± 2.7 | 24.9 ± 19.0 | 1.2 ± 1.7 | |
| AA | 3.7 ± 2.5 | 2.2 ± 2.4 | 4.0 ± 2.9 | 25.8 ± 20.4 | 1.3 ± 1.8 | |
| p | 0.101 | 0.636 | 0.156 | 0.915 | 0.896 | |
| Adjusted p* | 0.178 | 0.835 | 0.274 | 0.911 | 0.765 | |
| CC/AC | 4.3 ± 2.3 | 2.4 ± 2.2 | 4.7 ± 2.8 | 24.8 ± 18.6 | 1.2 ± 1.8 | |
| AA | 3.7 ± 2.5 | 2.2 ± 2.4 | 4.0 ± 2.9 | 25.8 ± 20.4 | 1.3 ± 1.8 | |
| p | 0.032 | 0.371 | 0.060 | 0.672 | 0.695 | |
| Adjusted p* | 0.072 | 0.842 | 0.184 | 0.867 | 0.562 | |
| IL-23R | AA | 3.9 ± 2.4 | 2.3 ± 2.2 | 4.3 ± 2.8 | 24.3 ± 19.0 | 1.1 ± 1.4 |
| CA | 4.5 ± 2.3 | 2.5 ± 2.3 | 4.9 + 2.9 | 26.1 ± 18.8 | 1.2 ± 1.6 | |
| CC | 3.6 ± 2.0 | 2.0 ± 2.1 | 4.0 ± 2.3 | 26.3 ± 21.1 | 1.1 ± 2.1 | |
| p | 0.055 | 0.471 | 0.097 | 0.655 | 0.772 | |
| Adjusted p* | 0.031 | 0.426 | 0.061 | 0.495 | 0.384 | |
| AA | 3.9 ± 2.4 | 2.3 ± 2.2 | 4.3 ± 2.8 | 24.3 ± 19.0 | 1.1 ± 1.4 | |
| CA/CC | 4.3 ± 2.3 | 2.4 ± 2.3 | 4.7 ± 2.8 | 26.2 ± 19.2 | 1.2 ± 1.7 | |
| p | 0.148 | 0.660 | 0.151 | 0.357 | 0.524 | |
| Adjusted p* | 0.086 | 0.318 | 0.090 | 0.238 | 0.169 |
↵* Adjusting the effects of age, sex, disease duration, and medication history. AS: ankylosing spondylitis; ESR: erythrocyte sedimentation rate; CRP: C-reactive protein; BASDAI: Bath Ankylosing Spondylitis Disease Activity Index; BASFI: Bath Ankylosing Spondylitis Functional Index; BAS-G: Bath Ankylosing Spondylitis Global.