Demographic characteristics of PsA patients at baseline, Week 12, and Week 52. Group 1 continued TNF blockers after 12 weeks. Group 2 discontinued TNF blockers after 12 weeks.
| Characteristic | Baseline | Week 12 | Week 52 | |||
|---|---|---|---|---|---|---|
| Group 1 (n = 9) | Group 2 (n = 11) | Group 1 (n = 9) | Group 2 (n = 11) | Group 1 (n = 9) | Group 2 (n = 11) | |
| Age, yrs | 47.8 (13.0) | 51.5 (11.1) | ||||
| Illness duration, yrs | 5.7 (5.7) | 9.5 (7.5) | ||||
| Sex, % male | 54 | 63.6 | ||||
| Tender joint (0–68) | 11.2 (6.0) | 9.8 (4.0) | 3.0 (6.1) | 3.4 (4.4) | 2.0 (3.5) | 7.0 (10.2) |
| Swollen joint (0–66) | 4.7 (1.6) | 2.9 (2.5) | 1.2 (1.9) | 1.1 (1.4) | 0 | 2.2 (0.7)** |
| DAS28 | 6.14 (0.83) | 5.55 (0.67) | 2.70 (1.37) | 2.83 (1.28) | 1.24 (0.44) | 1.38 (0.44)** |
| Pain (0–100) | 67.8 (23.3) | 62.7 (16.8) | 14.4 (10.1) | 33.2 (23.5)* | 20.6 (20.8) | 49.5 (26.5)* |
| PGA (0–100) | 67.8 (20.5) | 58.2 (16.6) | 28.9 (22.6) | 32.3 (22.1) | 22.3 (21.3) | 42.5 (25.5) |
| HAQ | 1.16 (0.59) | 1.02 (0.68) | 0.43 (0.53) | 0.80 (0.74) | 0.50 (0.18) | 0.86 (0.27) |
| SF-36 scales | ||||||
| PF | 51.5 (23.5) | 57.7 (21.8) | 76.7 (25.0) | 73.3 (22.1) | 70.6 (30.4) | 54.5 (28.0) |
| RP | 19.4 (34.9) | 20.5 (40.0) | 75.0 (35.6) | 69.4 (42.9) | 59.3 (42.1) | 25.0 (43.3) |
| BP | 30.7 (12.5) | 42.8 (21.4) | 71.6 (20.1) | 54.0 (17.1) | 67.8 (22.4) | 40.2 (19.2)** |
| GH | 23.8 (8.0) | 40.5 (11.0)** | 49.6 (20.4) | 47.1 (13.0) | 44.4 (25.2) | 27.5 (10.6) |
| VT | 43.9 (9.3) | 41.8 (11.2) | 55.6 (21.0) | 45.6 (15.3) | 52.8 (21.4) | 36.4 (19.0) |
| SF | 50.1 (29.2) | 55.9 (31.3) | 77.8 (21.4) | 77.8 (22.3) | 75.0 (18.8) | 52.2 (27.8) |
| RE | 29.6 (42.3) | 24.2 (39.7) | 81.5 (33.8) | 74.1 (43.4) | 62.5 (37.5) | 21.2 (40.2)* |
| MH | 50.7 (23.1) | 57.5 (11.5) | 60.0 (20.9) | 68.0 (11.1) | 61.5 (20.7) | 53.2 (15.1) |
| PCS | 22.3 (7.6) | 28.0 (9.3) | 41.9 (13.3) | 36.6 (10.5) | 41.2 (16.4) | 26.2 (13.9) |
| MCS | 38.8 (12.6) | 38.8 (9.2) | 48.0 (13.3) | 49.2 (9.9) | 44.8 (13.4) | 37.2 (11.0) |
DAS28: Disease Activity Score (28 joints); PGA: Patients assessment of global health; HAQ: Health Assessment Questionnaire; PF: physical functioning; RP: role limitation due to physical problem; BP: bodily pain; GH: general health; VT: vitality; SF: social functioning; RE: role limitation due to emotional problem; MH: mental health; PCS: physical component summary score; MCS: mental component score.
↵* If p < 0.05.
↵** If p < 0.01.