Cumulative incidence of extraarticular rheumatoid arthritis (ExRA) at 10-year followup after RA incidence in the 1985–1994 cohort (Rochester, Minnesota residents) and 1995–2007 cohort (Olmsted County, containing Rochester, Minnesota, residents).
| Extraarticular Manifestation | Period of RA Incidence | |||
|---|---|---|---|---|
| 1985–1994 (n = 147) | 1995–2007 (n = 463) | |||
| Number of Events* | 10-year Cumulative Incidence (%) | Number of Events* | 10-year Cumulative Incidence (%) | |
| Any ExRA | 64 | 46.2 | 184 | 50.1 |
| Severe ExRA* | 13 | 9.7 | 25 | 6.7 |
| Pericarditis | 2 | 2.0 | 8 | 2.6 |
| Pleuritis | 3 | 2.1 | 6 | 1.9 |
| Felty’s syndrome | 0 | 0 | 2 | 0.5 |
| Vasculitis** | 5 | 3.6 | 2 | 0.6 |
| Neuropathy | 2 | 1.4 | 6 | 1.2 |
| Mononeuropathy | 0 | 0 | 2 | 0.2 |
| Polyneuropathy | 2 | 1.4 | 4 | 1.0 |
| Scleritis | 0 | 0 | 0 | 0 |
| Episcleritis | 1 | 0.7 | 3 | 0.7 |
| Retinal vasculitis | 0 | 0 | 0 | 0 |
| Glomerulonephritis | 0 | 0 | 0 | 0 |
| Other ExRA | 60 | 43.4 | 169 | 45.7 |
| Amyloidosis | 0 | 0 | 0 | 0 |
| Keratoconjunctivitis sicca | 16 | 12.2 | 74 | 20.4 |
| Xerostomia | 1 | 0.7 | 2 | 0.5 |
| Sjögren’s syndrome | 13 | 9.7 | 38 | 9.6 |
| Pulmonary fibrosis | 9 | 6.6 | 15 | 5.0 |
| Bronchiolitis obliterans | 0 | 0 | 2 | 0.7 |
| Organizing pneumonia | 1 | 0 | 2 | 0.4 |
| Cervical myelopathy | 3 | 2.2 | 2 | 0.7 |
| Subcutaneous nodules | 43 | 31.2 | 110 | 31.2 |
| Other nodules | 0 | 0 | 1 | 0.2 |