Descriptive results of OA groups (sample-weighted).
| NOA, n = 33 | PROA, n = 124 | ROA, n = 98 | p* | |
|---|---|---|---|---|
| Median age, yrs (range) | 47.3 (40.1–79.9) | 53.8 (39.8–79.3) | 62.2 (45.2–79.8) | < 0.001 |
| Sex (% women) | 58 | 55 | 57 | 0.924** |
| Median BMI (range), kg/m2 | 24.1 (18.1–33.3) | 24.6 (18.7–41.3) | 26.5 (19.3–49.6) | 0.014 |
| Median BMLsum (range) | 0.0 (0–3) | 0.0 (0–5) | 2.0 (0–10) | < 0.001 |
| BMLmax > 0, % | 11 | 38 | 71 | < 0.001** |
| BMLmax = 0, % | 89 | 62 | 29 | < 0.001† |
| BMLmax = 1, % | 7 | 19 | 31 | < 0.001† |
| BMLmax = 2, % | 0 | 15 | 28 | < 0.001† |
| BMLmax = 3, % | 3 | 4 | 13 | < 0.001† |
| Median duration of knee pain, yrs (range) | 4.1 (0.7–3.0) | 5.0 (0–45) | 12.2 (0–65) | < 0.001 |
| Median frequency of knee pain, no. days/mo (range) | 20.0 (0–30) | 25.0 (0–30) | 30.0 (0–30) | 0.001 |
| Median total WOMAC pain (range) | 19.0 (0–26.0) | 12.0 (0–77.0) | 21.0 (0–74.8) | 0.001 |
| Median Pain on Walking (range) | 5.0 (0–61.0) | 5.0 (0–98.0) | 16.0 (0–96.0) | 0.001 |
| Median Pain on Climbing Stairs (range) | 18.0 (0–100) | 25.0 (0–100) | 37.0 (0–96.0) | 0.005 |
↵* Kruskal-Wallis test unless otherwise indicated.
↵** Pearson chi-squared test.
↵† Pearson chi-squared and Cochrane-Armitage trend tests. OA: osteoarthritis; NOA: no OA; PROA: preradiographic OA; ROA: radiographc OA; BMI: body mass index; BMLsum: sum of 6 bone marrow lesion scores; BMLmax: worst BML score at any region; WOMAC: Western Ontario and McMaster Universities OA Index.