Change in FACIT-Fatigue scale versus change in BILAG ratings.

	Baseline to Week 12 Change (n)	Mean (SD)	Effect Size^*	p^**
BILAG Cardiorespiratory change	Improved (40)	4.4 (9.3)	0.47	0.005
	Unchanged (182)	5.8 (11.4)	0.51	< 0.001
	Worsened (5)	−1.8 (5.9)	−0.31	0.532
BILAG Hematologic change	Improved (33)	9.5 (14.5)	0.66	< 0.001
	Unchanged (188)	4.7 (10.2)	0.46	< 0.001
	Worsened (6)	5.6 (7.8)	0.71	0.142
BILAG Mucocutaneous change	Improved (101)	4.5 (11.2)	0.40	< 0.001
	Unchanged (121)	6.4 (10.8)	0.59	< 0.001
	Worsened (5)	−0.6 (9.8)	−0.06	0.898
BILAG Neurological change	Improved (23)	6.2 (10.6)	0.59	0.010
	Unchanged (198)	5.2 (11.0)	0.48	< 0.001
	Worsened (6)	7.5 (12.6)	0.60	0.204
BILAG Renal change	Improved (1)	5.0 (—)	—	—
	Unchanged (217)	5.3 (11.0)	0.48	< 0.001
	Worsened (9)	7.5 (11.4)	0.66	0.084
BILAG Vasculitis change	Improved (25)	1.2 (10.9)	0.11	0.600
	Unchanged (200)	6.0 (11.1)	0.55	< 0.001
	Worsened (2)	1.0 (2.8)	0.35	0.705

↵* Mean change/SD of change in that group,
↵** t-test of null hypothesis that change is equal to zero. FACIT: Functional Assessment of Chronic Illness Therapy; BILAG: British Isles Lupus Assessment Group.