Markers of bone metabolism show changes in the main indices of bone metabolism: absolute (percentage differences) at baseline (T0), after 4 months (T1), and after 8 months (T2).
| Test | Unit | Time 0 | Time 1 | Time 2 | Difference T2 vs T0, % |
|---|---|---|---|---|---|
| Calcium | mg/100ml | 9.3 | 9.5 (+2.15) | 9.5 (0) | +2.15 |
| Phosphorus | mg/100ml | 3.3 | 3.1 (−6.06) | 3.2 (+3.22) | −3.03 |
| Total ALP | U/I | 86 | 108 (+25.58) | 111 (+2.77) | +29.06 |
| Bone ALP | μg/l | 12 | 20 (+66.66) | 13.3 (−33.5) | +10.83 |
| Osteocalcin | ng/ml | 11.9 | 15.7 (+31.93) | 12.5 (−20.38) | +5.04 |
| PTH | pg/ml | 54.1 | 43.00 (−20.51) | 31.9 (−25.81) | −41.03 |
| CTX-I | pg/ml | 164 | 158 (−3.65) | 152 (−2.53) | −7.31 |
ALP: alkaline phosphatase; PTH: parathyroid hormones; CTX-I: collagen cross-linked C-telopeptide-I.