Association of polymorphisms in the IRF5 gene with susceptibility to systemic juvenile idiopathic arthritis (JIA).
| SNP, Subject Subset | No. (%) with Genotype | Allelic Association | |||||
|---|---|---|---|---|---|---|---|
| Total | OR | (95% CI) | p | ||||
| rs729302 | AA | AC | CC | ||||
| Systemic JIA | 42 (51.9) | 33 (40.7) | 6 (7.4) | 81 | 0.84 | 0.56–1.24 | 0.37 |
| Control | 116 (61.1) | 57 (30.0) | 17 (8.9) | 190 | 1.0 | — | — |
| rs2004640 | GG | GT | TT | ||||
| Systemic JIA | 36 (44.4) | 36 (44.4) | 9 (11.1) | 81 | 1.05 | 0.71–1.55 | 0.80 |
| Control | 82 (43.2) | 85 (44.7) | 23 (12.1) | 190 | 1.0 | — | — |
| rs2280714 | CC | CT | TT | ||||
| Systemic JIA | 28 (34.6) | 44 (54.3) | 9 (11.1) | 81 | 1.19 | 0.81–1.73 | 0.38 |
| Control | 58 (30.5) | 94 (49.5) | 38 (20.0) | 190 | 1.0 | — | — |
IRF5: interferon regulatory factor 5; SNP: single-nucleotide polymorphism.