Validation study of association between rs3775369 and RA susceptibility in RIKEN/BioBank series and combined analysis.
| Genotypes of Patients | Genotypes of Controls | p | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Series | GG | GA | AA | Total | MAF | GG | GA | AA | Total | MAF | OR (95% CI) | Allele | Genotype |
| RIKEN/BioBank | 493 | 497 | 119 | 1109 | 0.331 | 442 | 416 | 76 | 934 | 0.304 | 1.13 (0.99–1.30) | 0.062 | 0.058 |
| IORRA | 681 | 669 | 145 | 1495 | 0.321 | 384 | 301 | 59 | 744 | 0.282 | 1.21 (1.05–1.38) | 0.0075 | 0.0070 |
| Combined | 1174 | 1166 | 264 | 2604 | 0.325 | 826 | 717 | 135 | 1678 | 0.294 | 1.17 (1.06–1.28) | 0.0015 | 0.0051 |
MAF: minor allele frequency.