Allele | Genotypes of Patients | Genotypes of Controls | p | |||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
SNP | Location | Position* | 1/2 | 1/1 | 1/2 | 2/2 | Total | MAF | 1/1 | 1/2 | 2/2 | Total | MAF | OR (95% CI) | Allele | Genotype |
rs3816056 | Intron 1 | 25986294 | G/T | 1072 | 383 | 39 | 1494 | 0.154 | 495 | 236 | 20 | 751 | 0.184 | 0.81 (0.69–0.96) | 0.012 | 0.012 |
rs3775369 | Intron 1 | 25980974 | G/A | 681 | 669 | 145 | 1495 | 0.321 | 384 | 301 | 59 | 744 | 0.282 | 1.21 (1.05–1.38) | 0.0075 | 0.0070 |
rs1501096 | Intron 1 | 25980569 | A/C | 1037 | 405 | 46 | 1488 | 0.167 | 480 | 247 | 24 | 751 | 0.196 | 0.82 (0.70–0.97) | 0.015 | 0.015 |
rs3796655 | Intron 1 | 25980365 | A/T | 1043 | 407 | 46 | 1496 | 0.167 | 480 | 247 | 24 | 751 | 0.196 | 0.82 (0.70–0.96) | 0.015 | 0.014 |
rs12501083 | Intron 1 | 25970515 | T/C | 1218 | 265 | 14 | 1497 | 0.098 | 617 | 127 | 7 | 751 | 0.094 | 1.05 (0.84–1.30) | 0.67 | 0.67 |
rs736517 | Intron 2 | 25946759 | G/C | 1057 | 396 | 43 | 1496 | 0.161 | 511 | 217 | 24 | 752 | 0.176 | 0.90 (0.76–1.06) | 0.20 | 0.20 |
↵* Positions are according to genomic contig NT_016354.18. MAF: minor allele frequency. IORRA: Institute of Rheumatology Rheumatoid Arthritis.