Maximal daily temperature, laboratory values, and treatments.
| Normal Values | 8 Months Prior to Admission: Spinal Surgery | 4 Months Prior to Admission: Diagnosis of AOSD | Admission for MAS | 3 Months After Admission | 10 Months After Admission | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Day 1 | Day 2 | Day 3 | Day 4 | Day 5 | Day 6 | Day 7 | Day 8 | ||||||
| Maximum temperature (°C) | ≤ 37.5 | 38.5 | 40.1 | 39.8 | 40 | 40.4 | 38.2 | 38.6 | 37.8 | 37.8 | 37.8 | < 37.5 | < 37.5 |
| WBC (×109 cells/l) | 4.0–11.0 | 5.7 | 19.6 | 16.2 | 11.6 | 7.1 | 4.2 | 3.3 | 5.6 | 6.5 | 7.4 | 4.8 | 6.4 |
| Hb (g/l) | 120–152 | 100 | 80 | 111 | 109 | 98 | 87 | 93 | 103 | 101 | 105 | 118 | 137 |
| Platelets (×109 cells/l) | 150–400 | 233 | 454 | 294 | 216 | 156 | 137 | 145 | 203 | 262 | 303 | 281 | 225 |
| ESR (mm/h) | < 20 | 35 | 64 | – | 8 | – | – | – | – | – | 13 | 18 | 7 |
| C-reactive protein (mg/l) | < 8 | – | 27 | – | 103 | – | – | – | – | – | 8 | 2 | < 1 |
| Ferritin (μg/l) | 10–150 | – | 866 | – | – | – | 7194 | – | – | – | 1552 | 11.3 | 7.9 |
| Treatment | Start antituberculous medication | ||||||||||||
| Start gold salts | Start methylprednisolone Start anakinra | ||||||||||||
AOSD: adult-onset Still’s disease; MAS: macrophage activation syndrome; WBC: white blood cells; Hb: hemoglobin; ESR: erythrocyte sedimentation rate.