Table 3.

Correlation coefficients between ACR core set measures and DAS28 determined at 12 to 24 week intervals and means of these variables over the 96 week period, and the increase in total Sharp score over 96 weeks.

	Initial	12 Weeks	24 Weeks	48 Weeks	72 Weeks	96 Weeks	Mean^#
CRP	0.292^*	0.477^***	0.562^***	0.521^***	0.479^***	0.227	0.573^***
ESR	0.235	0.491^***	0.402^**	0.350^*	0.055	0.028	0.380^**
MHAQ	0.138	0.183	0.210	0.250	0.246	0.005	0.272
Patients’ pain estimation^†	0.163	0.521^***	0.428^**	0.405^**	0.472^**	0.025	0.531^***
Patients’ global assessment^††	0.152	0.500^***	0.470^***	0.382^**	0.563^***	0.049	0.554^***
Swollen joint count	0.279^*	0.434^**	0.411^**	0.518^***	0.266	0.214	0.523^***
Tender joint count	0.085	0.257	0.149	0.202	0.240	0.031	0.275^*
Physicians’ global assessment^†††	0.253	0.449^***	0.478^***	0.453^***	0.419^**	0.101	0.524^***
DAS28-(CRP)	0.384^**	0.592^***	0.610^***	0.538^***	0.447^**	0.293^*	0.618^***

↵† Patients’ estimation of pain on visual analog scale (VAS).
↵†† Patients’ global assessment of disease activity on VAS.
↵††† Physicians’ global assessment of disease activity on VAS.
↵* p < 0.05;
↵** p < 0.01;
↵*** p < 0.001.
↵# Mean of values determined every 12 weeks over 96 week treatment period.