Table 3.

OPN levels in plasma and urine.

Levels of OPN, Median (range)ControlsOARA
U-half, pmol/mmol Cr67.9 (1.3–148.4)69.8 (5.8–430.7)143.5 (3.2–2431.8)*
U-full, ng/mmol Cr1549.2 (22.7–3949.4)945.7 (47.5–2358.9)2044.6 (54.8–8055.5)
P-full, ng/ml277.9 (114.0–655.1)413.9 (195.6–1047.8)*499.4 (58.8–1492.8)*
  • * p < 0.05 compared to healthy controls.

  • p < 0.05 compared to OA. OPN: osteopontin; U-half: thrombin-cleaved OPN in urine; U-full: full-length form of OPN in urine; P-full: full-length form of OPN in plasma.