Cutpoint | ||||
---|---|---|---|---|
150 Days (5 months) | Very Early vs Very Late | |||
Early, < 150 Days, N = 110 | Late, ≥ 150 Days, N = 123 | Early, < 90 Days, N = 51 | Late, ≥ 300 Days, N = 49 | |
No. months on MTX (n = 183) | 15.1 (8.1) | 15.7 (7.2) | 13.84 (8.24) | 17.4 (7.4) |
Mg/wk | 13.2 (8.4) | 12.3 (6.1) | 14.88 (11.78) | 13.5 (6.7) |
n (%) | 93 (84.5) | 90 (73.2) | 40 (78.4) | 33 (67.3) |
No. of months on HCQ (n = 182) | 11.0 (8.5) | 14.3 (8.0) | 9.14 (8.05) | 15.0 (8.4)* |
mg/day | 374.6 (109.9) | 340.9 (102.3)* | 362.37 (143.0) | 312.8 (87.6) |
n (%) | 43 (39.1) | 65 (52.8) | 21 (41.2) | 26 (53.1) |
No. months on prednisone (n = 147) | 14.1 (8.1) | 14.6 (8.7) | 12.78 (7.33) | 17.15 (7.2)* |
Mg/day | 6.5 (3.0) | 6.29 (3.7) | 6.62 (2.72) | 5.4 (2.3) |
n (%) | 73 (66.4) | 74 (60.2) | 31 (60.8) | 27 (55.1) |
No. months on SSZ (n = 50) | 13.0 (8.6) | 11.8 (7.9) | 16.36 (7.62) | 9.5 (8.5) |
Mg/day | 1845.5 (735.3) | 1742.3 (587.7) | 1763.30 (646.0) | 1835.0 (660.3) |
n (%) | 26 (23.6) | 24 (19.5) | 14 (27.5) | 10 (20.4) |
MTX+HCQ, no. patients (%) | 12 (10.9) | 13 (10.6) | 5 (9.8) | 5 (10.2) |
MTX+PRED, no. patients (%) | 25 (22.7) | 21 (17.0) | 10 (19.6) | 8 (16.3) |
↵* Significantly different at p < 0.05, earlier versus later institution of DMARD, using the Wilcoxon rank-sum test for continuous variables and chi-square test for categorical variables.