Table 2.

Disease activity scores and inflammatory mediators throughout the study in DAS28 responders and nonresponders.

DAS28 RespondersDAS28 Nonresponders
Baseline2 months4 monthspBaseline2 months4 monthsp
No. tender joints19 ± 7*7 ± 64 ± 4< 0.000112 ± 8*9 ± 811 ± 90.135
No. swollen joints9 ± 44 ± 32 ± 2< 0.00019 ± 56 ± 46 ± 30.021
DAS28-CRP6.46 ± 0.68*4.03 ± 1.153.46 ± 0.82< 0.00015.39 ± 1.51*4.71 ± 1.414.99 ± 1.380.023
Log10CRP, mg/l1.30 ± 0.410.87 ± 0.380.8 ± 0.35< 0.00011.21 ± 0.501.09 ± 0.511.13 ± 0.550.493
PV, mPa.s1.82 ± 0.181.67 ± 0.971.74 ± 0.150.0081.81 ± 0.191.79 ± 0.221.77 ± 0.220.438
HAQ1.87 ± 0.52*1.67 ± 0.521.44 ± 0.760.0011.42 ± 0.84*1.51 ± 0.701.44 ± 0.690.224
  • Values are mean ± SD.

  • * p < 0.05 between DAS28 responders and nonresponders at baseline. DAS28: Disease Activity Score of 28 joints; CRP: C-reactive protein; PV; plasma viscosity; HAQ: Stanford Health Assessment Questionnaire.