Table 1.

Characteristics of the patients with systemic sclerosis.

PatientsSSc Cohort, n = 659
Age, yrs ± SD59 ± 11
Female, n (%)574 (87)
Disease duration, yrs ± SD11 ± 8
Diffuse cutaneous subtype, n (%)247 (37)
Pulmonary fibrosis, n (%)263 (40)
DLCO/VA < 75%, n (%)291 (44)
Pulmonary arterial hypertension (defined by right heart catheterization, n (%)51 (8)
Digital ulcerations, n (%)199 (30)
Positive anti-topoisomerase I antibodies, n (%)163 (25)
Positive anti-centromere antibodies, n (%)270 (41)
  • DLCO/VA: diffusing capacity for carbon monoxide divided by alveolar volume.