Characteristic | NCP Present, n = 21 | NCP Absent, n = 18 | p | p Adjusted for Age |
---|---|---|---|---|
Demographics | ||||
Age (mean ± SD), yrs | 54.0 ± 9.6 | 46.3 ± 7.9 | 0.01 | |
Ethnicity (% African American) | 29 | 33 | 1.0 | 0.94 |
Gender (% women) | 86 | 94 | 0.61 | 0.18 |
Serologies | ||||
Anti-Sm (% ever positive) | 10 | 11 | 1.0 | 0.85 |
Anti-RNP (% ever positive) | 24 | 22 | 1.0 | 0.49 |
Anticardiolipin (% ever positive) | 76 | 56 | 0.20 | 0.077 |
Lupus anticoagulant (% ever positive) | 5 | 11 | 0.59 | 0.49 |
Inflammatory markers | ||||
Erythrocyte sedimentation rate, mm/h ± SD | 31.1 ± 31.4 | 25.3 ± 29.6 | 0.56 | 0.34 |
hs-CRP, mg/l ± SD | 4.10 ± 5.91 | 3.27 ± 6.46 | 0.68 | 0.76 |
Treatment | ||||
Prednisone use (% ever) | 90 | 83 | 0.65 | 0.30 |
Prednisone use (% currently using) | 43 | 33 | 0.74 | 0.32 |
Hormone replacement therapy (% ever) | 61 | 12 | < 0.005 | 0.02 |
Hormonal replacement therapy (% currently using) | 50 | 12 | 0.028 | 0.08 |
NSAID use (% ever using) | 76 | 61 | 0.49 | 0.28 |
NSAID use (% currently using) | 52 | 17 | 0.043 | 0.041 |
Immunosuppressive drug use (% currently using) | 48 | 17 | 0.051 | 0.024 |
Hydroxychloroquine use (% ever) | 95 | 78 | 0.16 | 0.15 |
Hydroxychloroquine use (% currently using) | 86 | 78 | 0.68 | 0.70 |
hs-CRP: high-sensitivity C-reactive protein; NSAID: nonsteroidal antiinflammatory drug.