ACR criteria for SLE in 6 patients exposed to TNF inhibitors.
| SLE Criterion | Patients | |||||
|---|---|---|---|---|---|---|
| 1 | 2 | 3 | 4 | 5 | 6 | |
| Malar rash | + | − | + | + | + | − |
| Discoid rash | − | − | + | − | − | − |
| Photosensitivity | + | + | + | + | + | + |
| Oral ulcer | − | − | − | − | − | − |
| Arthritis | + | + | + | + | − | + |
| Serositis | Pericarditis | − | − | − | + | − |
| Renal disorder | − | − | − | − | − | + |
| Neurologic disorder | − | Optic neuritis | Headaches, major depression | − | Major depression | − |
| Immunologic disorders* | Anticardiolipin antibodies | Anti-ds DNA antibodies | − | Anti-ds DNA antibodies | − | Anti-ds DNA, SSA/SSB antibodies |
| Hematologic disorders | − | − | − | − | − | − |
| Positive ANA** | Speckled 1:6250 | Homogenous 1:6250 | Homogenous 1:6250 | Nucleolar 1:6250 | Homogenous 1:6250 | Homogenous 1:6250 |