Sensitivities, specificities, positive (LR+), and negative likelihood ratios (LR−) for temporal artery ultrasonography (TA-US) findings versus TAB-proven or clinically defined GCA. Values in parentheses are the 95% CI.
| TAB-Proven GCA | Clinically Defined GCA | |||||||
|---|---|---|---|---|---|---|---|---|
| Sensitivity, % | Specificity, % | LR+ | LR− | Sensitivity, % | Specificity, % | LR+ | LR− | |
| Doppler and duplex TA-US, n = 77 | ||||||||
| Stenosis | 62 (36–82) | 70 (58–80) | 2.1 (1.2–3.7) | 0.5 (0.3–1.1) | 47 (27–68) | 69 (56–79) | 1.5 (0.8–2.8) | 0.8 (0.5–1.2) |
| Occlusion | 15 (4–42) | 84 (74–91) | 1.0 (0.2–4.0) | 1.0 (0.8–1.3) | 11 (3–31) | 83 (71–90) | 0.6 (0.1–2.5) | 1.1 (0.9–1.3) |
| Any stenosis and/or occlusion | 69 (42–87) | 59 (47–71) | 1.7 (1.1–2.7) | 0.5 (0.2–1.2) | 53 (32–73) | 57 (44–69) | 1.2 (0.7–2.1) | 0.8 (0.5–1.4) |
| Any stenosis and/or occlusion (seen bilaterally) | 23 (8–50) | 88 (77–94) | 1.8 (0.6–6.0) | 0.9 (0.6–1.2) | 16 (6–38) | 86 (75–93) | 1.1 (0.3–3.9) | 1.0 (0.8–1.2) |
| Duplex TA-US, n = 31 | ||||||||
| Halo sign | 17 (3–56) | 100 (87–100) | Infinite (NA) | 0.8 (0.6–1.2) | 10 (2–40) | 100 (85–100) | Infinite (NA) | 0.9 (0.7–1.1) |
| Any stenosis, occlusion, and/or halo | 50 (19–81) | 72 (52–86) | 1.8 (0.6–4.9) | 0.7 (0.3–1.6) | 20 (6–51) | 62 (41–79) | 0.5 (0.1–2.0) | 1.3 (0.8–2.0) |
| Any stenosis, occlusion, and/or halo (seen bilaterally) | 17 (3–56) | 96 (80–99) | 4.2 (0.3–57.5) | 0.9 (0.6–1.3) | 10 (2–40) | 95 (77–99) | 2.1 (0.1–30.3) | 0.9 (0.8–1.2) |
NA: not applicable. TAB: temporal artery biopsy; GCA: giant cell arteritis.