Sensitivity analysis of the effect size on depressed mood at posttreatment.
| Outcome | No. Study Arms | No. Patients | Effect Size, SMD (95% CI) | Test for Overall Effect, p | Heterogeneity, I2 (%); Tau2 |
|---|---|---|---|---|---|
| Sequence generation | |||||
| Adequate | 5 | 268 | −0.31 (−0.56, −0.07) | 0.01 | 0; 0 |
| Unclear or inadequate | 6 | 363 | −0.18 (−0.39, 0.04) | 0.11 | 0; 0 |
| Concealment of allocation | |||||
| Adequate | 2 | 91 | −0.08 (−0.49, 0.33) | 0.70 | 0; 0 |
| Unclear or inadequate | 9 | 540 | −0.26 (−0.44, −0.07) | 0.006 | 0; 0 |
| Intent-to-treat analysis | |||||
| Yes | 7 | 398 | −0.19 (−0.40, 0.01) | 0.07 | 0; 0 |
| No | 4 | 233 | −0.31 (−0.57, −0.05) | 0.02 | 0; 0 |
| Treatment quality | |||||
| Poor | 3 | 180 | −0.12 (−0.56, 0.33) | 0.33 | 55; 0.05 |
| Average | 4 | 240 | −0.36 (−0.62, −0.09) | 0.008 | 0; 0 |
| Excellent | 4 | 211 | −0.21 (−0.49, 0.07) | 0.14 | 0; 0 |
| Patients with affective and anxiety disorders included | |||||
| Yes | 6 | 358 | −0.20 (−0.42, 0.01) | 0.07 | 3; 0 |
| No | 5 | 273 | −0.28 (−0.53, −0.04) | 0.02 | 0; 0 |
| Public period | |||||
| Until 2000 | 4 | 238 | −0.20 (−0.54, 0.14) | 0.124 | 42; 0.05 |
| 2000–2005 | 3 | 131 | −0.10 (−0.44, 0.24) | 0.56 | 0; 0 |
| 2006–2009 | 4 | 262 | −0.36 (−0.62, −0.10) | 0.006 | 0; 0 |
SMD: Standardized mean difference.