Immunofluorescence patterns and titers of positive autoimmune target test in negative ANA samples.
| Titer ≤ 1:160 | N | Titer ≥ 1:320 | N |
|---|---|---|---|
| MTOC | 116 | Speckled | 22 |
| MTOC + speckled | 43 | Diffuse granular | 20 |
| Diffuse granular | 17 | MTOC | 7 |
| Cytoskeleton | 13 | MTOC + diffuse granular | 3 |
| MTOC + diffuse granular | 6 | MTOC + speckled | 2 |
| GiM | 6 | Discrete speckled (centromere) | 2 |
| Centriole | 4 | ||
| Others | 8 | Others | 6 |
| Total | 213 | Total | 62 |
ANA: antinuclear antibody; MTOC: microtubule organizing center; GiM: granules in macrophage (MTOC and GiM are new patterns that had not been reported in HEp-2 cell line7,8).