Pack-years | Infliximab | Etanercept | ||||
---|---|---|---|---|---|---|
Response, n (%) | No Response, n (%) | OR (95% CI) | Response, n (%) | No Response, n (%) | OR (95% CI) | |
3 months | ||||||
0 | 32 (100) | 0 (0) | 1.0 (ref) | 11 (78.6) | 3 (21.4) | 1.0 (ref) |
1–15 | 18 (85.7) | 3 (14.3) | 12.3 (0.7–53) | 19 (86.4) | 3 (13.6) | 0.6 (0.07–4.5) |
16–30 | 15 (75.0) | 5 (25.0) | 23.1 (1.6–109) | 9 (90.0) | 1 (10.0) | 0.5 (0.01–6.02) |
> 30 | 8 (80.0) | 2 (31.8) | 19.1 (0.8–75)** | 6 (66.7) | 3 (33.3) | 1.8 (0.2–17.7) |
12 months | ||||||
0 | 19 (58.1) | 13 (41.9) | 1.0 (ref) | 9 (72.7) | 5 (27.3) | 1.0 (ref) |
1–15 | 11 (52.4) | 10 (47.6) | 1.3 (0.4–3.9) | 12 (52.9) | 10 (47.1) | 1.5 (0.4–5.5) |
16–30 | 9 (45.0) | 11 (55.0) | 1.7 (0.6–5.3) | 8 (75.0) | 2 (25.0) | 0.5 (0.1–2.9) |
> 30 | 2 (20.0) | 8 (80.0) | 4.9 (1.0–23.6)* | 2 (22.2) | 7 (77.8) | 5.2 (0.9–30.6) |