Relationship between pack-year history and response to TNF antagonists.
| Pack-years | Response, n (%) | No Response, n (%) | Odds Ratio (95% CI) |
|---|---|---|---|
| 3 months | |||
| 0 | 48 (94.1) | 3 (5.9) | 1.0 (ref) |
| 1–15 | 42 (84.0) | 8 (16.0) | 2.8 (0.7–10.3) |
| 16–30 | 25 (78.1) | 7 (21.9) | 4.1 (1.04–15.8) |
| > 30 | 15 (68.2) | 6 (31.8) | 5.8 (1.4–24.0)* |
| 12 months | |||
| 0 | 33 (66.0) | 18 (34.0) | 1.0 (ref) |
| 1–15 | 26 (50.0) | 24 (50.0) | 1.7 (0.8–3.7) |
| 16–30 | 18 (51.7) | 14 (48.3) | 1.4 (0.6–3.5) |
| > 30 | 4 (19.0) | 17 (81.0) | 7.0 (2.2–22.9)** |