Regression models for the concurrent and longitudinal association between renal activity and quality of life (QOL).
| QOL Outcomes | Multiple Regression Model* Coefficient† (95% CI) | Hierarchical Model** Coefficient†† (95% CrI) |
|---|---|---|
| Physical function | −2.04 (−3.24, −0.88) | −6.68 (−19.56, 6.24) |
| Role physical | −5.28 (−7.76, −2.76) | −3.08 (−18.64, 12.44) |
| Bodily pain | −1.08 (−2.52, 0.32) | −1.08 (−8.76, 6.64) |
| Vitality | −0.96 (−2.20, 0.24) | 1.2 (−7.96, 10.36) |
| Role emotional | −1.20 (−3.68, 1.32) | −3.6 (−18.92, 11.72) |
| Mental health | −0.52 (−1.56, 0.56) | −0.76 (−7.52, 4.6) |
| Social function | −2.24 (−3.80, −0.72) | −5.44 (−18.04, 7.16) |
| General health | −0.76 (−1.88, 0.36) | −3.84 (−12.44, 4.76) |
| Physical component summary | −1.16 (−1.72, −0.60) | −2.56 (−6.52, 1.40) |
| Mental component summary | −0.16 (−0.80, 0.52) | −0.4 (−4.68, 3.92) |
CI: confidence interval; CrI: credible interval.
↵* This regression model examines the concurrent association between renal activity and each QOL outcome, adjusting for the potential confounders of age, sex, ethnicity (Caucasian vs non-Caucasian), marital status (married vs unmarried), education (continuous variable), disease duration, nonrenal SLEDAI, and nonrenal SLICC/ACR-DI. The nonrenal SLEDAI and SLICC/ACR-DI scores were measured at Time t and the other covariates at study entry only.
↵** This hierarchical model examines the longitudinal association between change in renal activity and change in each QOL outcome, adjusting for the potential confounders of age sex, ethnicity (Caucasian vs non-Caucasian), marital status (married vs unmarried), education (continuous variable), disease duration, renal and nonrenal SLEDAI, nonrenal SLICC/ACR-DI, and the outcome variable, all measured at study entry only.
↵† Coefficient expresses the association between the renal activity score and the specified QOL outcome.
↵†† Coefficient expresses the association between the longitudinal change in renal activity and change in the specified QOL outcome.