Unadjusted and multivariable adjusted† least-means squared scores (with 95% confidence intervals) for health related quality of life (HRQOL) and functional limitation in patients with and without spondyloarthritis (SpA).
| Unadjusted Scores | Adjusted Scores | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| No SpA | AS | PsA | ReA | p | No SpA | AS | PsA | ReA | p | |
| SF-36V summary | ||||||||||
| PCS | 35.3 (35.1, 35.4) | 28.9 (26.3, 31.4) | 34.1 (33, 35.3) | 36.8 (29.9, 43.6) | <0.0001 | 35 (34.9, 35.2) | 27.7 (25.3, 30.1) | 34.4 (33.3, 35.4) | 32.9 (26.4, 39.3) | <0.0001 |
| MCS | 46.1 (46, 46.2) | 47.9 (45.1, 50.7) | 45.6 (44.4, 46.8) | 40.6 (33, 48.1) | 0.2341 | 46 (45.8, 46.1) | 47.7 (45, 50.4) | 45.8 (44.6, 47) | 42 (34.8, 49.2) | 0.4195 |
| SF-36V subscales | ||||||||||
| PF | 50.4 (50.1, 50.8) | 39.2 (32.9, 45.5) | 48.4 (45.6, 51.1) | 58.5 (40.4, 76.6) | 0.0018 | 50.4 (50, 50.7) | 36.3 (30.5, 42) | 49.6 (47.1, 52.1) | 45.8 (29.3, 62.4) | <0.0001 |
| RP | 48.7 (48.4, 49.1) | 36.4 (30.1, 42.7) | 47.4 (44.6, 50.1) | 48.3 (30.2, 66.4) | 0.0014 | 48.6 (48.4, 49) | 34.3 (28.4, 40.3) | 48.6 (46, 51.2) | 38.9 (21.9, 55.9) | <0.0001 |
| BP | 49.6 (49.4, 50) | 36.9 (31.5, 42.2) | 47.3 (45, 49.6) | 42.2 (27, 57.3) | <0.0001 | 49.7 (49.3, 49.9) | 36 (30.8, 41.2) | 48 (45.8, 50.1) | 41.3 (26.5, 56.1) | <0.0001 |
| GH | 49.4 (49.1, 49.7) | 41.8 (36.9, 46.7) | 47.7 (45.6, 49.8) | 49.3 (35.4, 63.2) | 0.0089 | 49.3 (49, 49.5) | 40.7 (36.1, 45.4) | 48.7 (46.7, 50.7) | 46 (32.8, 59.2) | 0.0042 |
| VT | 44.4 (44.1, 44.6) | 40.8 (36, 45.6) | 43.8 (41.7, 45.8) | 36.8 (23, 50.4) | 0.3014 | 44.4 (44.1, 44.6) | 40.4 (35.7, 45) | 44.6 (42.6, 46.6) | 35.8 (22.6, 49) | 0.2103 |
| SF | 62.6 (62.3, 62.9) | 58 (51.8, 64.1) | 61.6 (58.9, 64.2) | 51.1 (33.5, 68.8) | 0.22 | 62.6 (62.3, 62.9) | 57.3 (51.4, 63.2) | 62.5 (60, 65.1) | 50.5 (33.4, 67.6) | 0.18 |
| RE | 64 (63.6, 64.3) | 64.4 (57.8, 70.9) | 62.5 (59.8, 65.3) | 57.6 (39.2, 75.9) | 0.69 | 63.9 (63.5, 64.2) | 62.1 (55.9, 68.5) | 63.5 (60.9, 66.2) | 51.8 (34.2, 69.3) | 0.53 |
| MH | 66.9 (66.7, 67.2) | 68.1 (63.4, 72.7) | 66.1 (64, 68.1) | 61.3 (48.4, 74.1) | 0.65 | 66.8 (66.5, 67) | 67.9 (63.5, 72.3) | 66.5 (64.6, 68.5) | 64.5 (52.3, 76.8) | 0.93 |
| % with difficulty in each ADL | ||||||||||
| Bathing | 24 (23.6, 24.5) | 36.4 (27, 46.9) | 26 (22, 30.1) | 20 (5, 54.1) | 0.056 | 25.7 (24, 27.4) | 41.2 (30.8, 52.4) | 26.8 (22.6, 31.5) | 29.5 (8, 66.6) | 0.0265 |
| Dressing | 22.4 (22, 22.9) | 42.7 (32.9, 53.1) | 23.6 (20, 27.6) | 20 (5, 54.1) | 0.0004 | 22.1 (20.5, 23.6) | 43.8 (33.5, 54.6) | 22.6 (18.8, 26.9) | 23.7 (6.1, 59.8) | 0.0002 |
| Eating | 12.6 (12.2, 13) | 22.1 (14.6, 32.1) | 10.9 (8.3, 14.1) | 18.1 (4.5, 50.7) | 0.0572 | 14 (12.8, 15.3) | 25.6 (16.9, 36.7) | 11.8 (8.9, 15.4) | 21.7 (5.6, 56.5) | 0.0265 |
| Getting in/out of chair | 38.4 (37.9, 38.9) | 55.1 (44.6, 65) | 42.7 (38.3, 47.3) | 54.5 (26.8, 79.7) | 0.002 | 38.8 (37, 40.6) | 57.4 (46.7, 67.5) | 42.3 (37.5, 47.3) | 64.1 (35, 85.5) | 0.0006 |
| Walking | 50.6 (50, 51.1) | 68.9 (58.6, 77.6) | 54.8 (50.3, 59.3) | 54.5 (26.8, 79.7) | 0.0013 | 53.7 (52, 55.6) | 74 (64.1, 81.9) | 56.6 (51.6, 61.4) | 67.2 (38.1, 87.1) | 0.0005 |
| Using toilet | 14.9 (14.6, 15.3) | 25.3 (17.2, 35.4) | 16.2 (13.1, 20) | 18.8 (4.5, 50.7) | 0.0754 | 13.7 (12.5, 15.1) | 24.4 (16.4, 34.7) | 14.5 11.5, 18.2) | 21.6 (5.5, 56.4) | 0.0508 |
| Number of ADL with limitation | 1.6 (1.6, 1.6) | 2.5 (2.1, 2.9) | 1.7 (1.5, 1.9) | 1.8 (0.7, 2.9) | <0.0001 | 1.6 (1.6, 1.6) | 2.5 (2.1, 2.9) | 1.7 (1.5, 1.8) | 2.1 (1, 3.2) | <0.0001 |
Bold values represent statistically significant results.
↵† Multivariable regression models adjusted for the following variables: age, sex, race, education level, marital status, employment status, comorbidity, and current smoking status. AS: ankylosing spondylitis; PsA: psoriatic arthritis; ReA: reactive arthritis; VR36: Short-Form-36; PCS: physical component summary; MCS: mental component summary; ADL: Activity of daily living; PF: physical functioning; RP: role physical; BP: bodily pain; GH: general health; VT: vitality; SF: social functioning; RE: role emotional; MH: mental health.