Table 3

Characteristics of those RA and SLE patients with elevated levels of anti-TNF anti-body. Each of the 6 patients with RA who had radiographs of their hands or feet had elevated levels of anti-TNF antibody and no erosions.

Diagnosis	RA	RA	RA	RA	RA	RA	RA	SLE	SLE	SLE	SLE
Anti-TNF (OD)	0.394	0.407	0.429	0.480	0.492	0.666	0.769	0.417	0.671	0.830	0.534
Age, yrs	68	72	34	38	86	77	65	23	23	28	38
Age at onset, yrs	35		29	35	70	65	60	21	21	19	20
Disease duration, yrs	33		5	3	16	12	5	2	2	9	18
History of smoking	Yes	No	No	No		No	Yes			Yes	No
Erosions	No		No	No	No	No	No
CRP, mg/dl	0.9	4.2	2.9	9		1.8	7	1	2.5	0.7	0.8
ESR	20	39	35	72	27	15	9	82	88	14	19
RF	19		157	2130	4	0	3460
CCP	1	2	2416	15	1	2	1
DMARD	Yes	No	Yes	No	Yes	Yes
Plaquenil								No	No	Yes	Yes
Prednisone	No	Yes				Yes	No	Yes	No	Yes	Yes
White cell count								7.93	5.14	4.71	5.09
Hemoglobin								11.3	10.2	13.5	13.8
Active SLE skin								No	No	No
Active SLE arthritis								No	Yes	No
Active SLE renal								Yes	No	No
Anti-DNA								30	121	16	317
Anti-SM								4	0	13	14
Anti-RNP								10	0	0	28
Anti-Ro								157		2	166
Anti-La								156		1	32

OD: optical density; CRP: C-reactive protein; ESR: erythrocyte sedimentation rate; RF: rheumatoid factor; CCP: cyclic citrullinated peptides; DMARD: disease modifying antirheumatic drugs.